Cell cycle, checkpoints and apoptosis
CELL CYCLE, CHECKPOINTS AND APOPTOSIS · IMAT Doutor1 / 1
A cell line carries an inactivating mutation in p53 in both alleles and is irradiated with a dose that breaks both DNA strands. The most likely outcome is:
A
The cell arrests permanently in G1
B
The cell undergoes apoptosis faster than a normal cell
C
DNA repair becomes more efficient than normal
D
The cell stops replicating its DNA but completes mitosis normally
E
The cell continues through the cycle and passes the damage on to its descendants
Keyboard: A–E to choose, Shift + letter to cross out, Enter to confirm.