IMAT 2026 · Question 28

Q28 - Mendelian and classical genetics

Which of the following statements about the chromosomal theory of inheritance is true? A) Chromosome segregation does not occur during meiosis B) Genes are independent of chromosomes C) Chromosomes do not contain genes D) Genes are found only in RNA E) Genes are located on chromosomes
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The correct answer is E) Genes are located on chromosomes.

The chromosomal theory (Sutton and Boveri, 1902) states that genes are carried on chromosomes. The way homologous chromosomes separate in meiosis explains Mendel’s laws. Morgan later confirmed it with fruit flies, linking eye colour to the X chromosome.

A) Incorrect: Homologous chromosomes do segregate in meiosis (anaphase I). This is the physical basis of Mendel’s law of segregation.

B) Incorrect: Genes are segments of DNA located on chromosomes, not independent of them.

C) Incorrect: This contradicts the theory: chromosomes are exactly where genes are.

D) Incorrect: In cells, genes are made of DNA. Some viruses do have RNA genes, but “only in RNA” is false.

E) Correct: Genes are located on chromosomes.

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